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MYP_178090
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Basic Information
VEGF-P3-CYC
Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Anti-angiogenic
Standard
23 amino acids
-
Standard
Sequence
ITMQCGIHQGQHPKIRMICEMSF
Physicochemical Analysis
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0434338 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
VEGF-derived peptide mimic
32630
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
L-amino-acid peptide [L]
Acetylation
Amidation
5-19
Bio-Activity Profile
Anti-angiogenic
Mus musculus (BALB/c mouse aortic rings)
Mouse aortic ring microvascular outgrowth assay (10 d)
PaperCombined vaccination with HER-2 peptide followed by therapy with VEGF peptide mimics exerts effective anti-tumor and anti-angiogenic effects in vitro and in vivo. PMID23170253 Evidence URLhttps://pmc.ncbi.nlm.nih.gov/articles/PMC3494619/
RECORD: Rec_0434339 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
VEGF-derived peptide mimic
32630
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
L-amino-acid peptide [L]
Acetylation
Amidation
5-19
Bio-Activity Profile
Anti-angiogenic
Mus musculus (BALB/c mouse Matrigel plugs)
Matrigel plug VE-cadherin mRNA expression by RT-PCR (10 d)
PaperCombined vaccination with HER-2 peptide followed by therapy with VEGF peptide mimics exerts effective anti-tumor and anti-angiogenic effects in vitro and in vivo. PMID23170253 Evidence URLhttps://pmc.ncbi.nlm.nih.gov/articles/PMC3494619/