MYP_178087
ImKTx104-D14A
Membrane / Ion-channel modulation
▸
Potassium channel modulation
▸
Potassium channel inhibitor
Standard
27 amino acids
-
Standard
ACVTHEDCTLLCYATIGTCVDGKCKCM
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0434229
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
ImKTx104 site-directed alanine-substitution variant
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Ion channel modulation
Potassium channel inhibitor
KCNQ1 potassium channel inhibitor
KCNQ1 (Kv7.1) potassium channel
25.6 % inhibition
Whole-cell patch-clamp channel-current assay