MYP_178082
Tsetse thrombin inhibitor (TTI, native mature peptide)
Enzyme modulation
▸
Enzyme inhibition
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Protease inhibition
Enzyme modulation
▸
Enzyme inhibition
▸
Thrombin inhibition
▸
Thrombin inhibitory
Hemostasis
▸
Anticoagulant activity
Hemostasis
▸
Antithrombotic activity
Standard
32 amino acids
-
Standard
GEPGAPIDYDEYGDSSEEVGGTPLHEIPGIRL
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_178078
VERIFIED: YES
Provenance & Taxonomy
Glossina morsitans morsitans [Animal]
Tsetse thrombin inhibitor
37546
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Native salivary-gland isolate; subsequent studies identify tyrosine O-sulfation in mature TTI. The 1996 Ki* is not assigned to a defined synthetic sulfation variant.
Bio-Activity Profile
Anticoagulant
Anti-thrombotic
Thrombin inhibitor
Protease inhibitor
Human thrombin
584 fM
Ki*