Peptide Database

Peptide NameScorpion K+ toxin AamTX1

Function Ontology

Membrane / Ion-channel modulation ▸ Ion channel inhibition ▸ Potassium channel inhibition

Venom / Toxin ▸ Neurotoxin ▸ Scorpion neurotoxin

Standard StatusStandard

Sequence Length59 amino acids

Chemical Formula-

DescriptionStandard

        MKFSSIILLTLLICSMSIFGNGQVQTNKKCKGGSCASVCAKEIGVAAGKCINGRCVCYP
    

Molecular Weight6146.39 Da

Isoelectric Point (pI)8.83

Net Charge (pH 7.0)5.56

GRAVY Index0.55

Boman Index0.00

Instability Index26.28

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_178080 VERIFIED: YES

Provenance & Taxonomy

OrganismAndroctonus amoreuxi [Animal]

FamilyScorpion potassium channel toxin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Ion channel modulation Potassium channel inhibitor Neurotoxin Scorpion venom peptide

TargetKv1.1 potassium channel

Activity50-500 nM

MethodPatch-clamp electrophysiology