Peptide Database

Peptide NameTsetse thrombin inhibitor (TTI)

Function Ontology

Annotation / Classification ▸ Source-based annotation ▸ Insect salivary peptide

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Sensory / Food function ▸ Hematophagy

Standard StatusStandard

Sequence Length53 amino acids

Chemical Formula-

DescriptionStandard

        MKFFTVLFFLLSIIYLIVAAPGEPGAPIDYDEYGDSSEEVGGTPLHEIPGIRL
    

Molecular Weight5799.60 Da

Isoelectric Point (pI)3.79

Net Charge (pH 7.0)-5.90

GRAVY Index0.44

Boman Index0.00

Instability Index36.62

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_178078 VERIFIED: YES

Provenance & Taxonomy

OrganismGlossina morsitans morsitans [Animal]

FamilyTsetse thrombin inhibitor

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsNative mature TTI contains O-sulfated tyrosine

Bio-Activity Profile

Function

Anticoagulant Anti-thrombotic Thrombin inhibitor Protease inhibitor

TargetHuman thrombin

Activity584 fM

MethodKi