Peptide Database

Peptide Nameα-Conotoxin GID

Function Ontology

Membrane / Ion-channel modulation ▸ Ion channel inhibition ▸ Acetylcholine receptor inhibition

Venom / Toxin

Venom / Toxin ▸ Conotoxin

Standard StatusStandard

Sequence Length10 amino acids

Chemical Formula-

DescriptionStandard

        GFRSPCPPFC
    

Molecular Weight1110.31 Da

Isoelectric Point (pI)8.16

Net Charge (pH 7.0)0.87

GRAVY Index0.01

Boman Index0.00

Instability Index147.12

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_178075 VERIFIED: YES

Provenance & Taxonomy

OrganismConus zonatus [Animal]

FamilyA-superfamily conotoxin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Ion channel modulation Nicotinic acetylcholine receptor inhibitor Neurotoxin Venom peptide Conotoxin

TargetnAChR (alpha7 subtype)

Activity1-10 nM

MethodTwo-electrode voltage clamp