Peptide Database

Peptide NameCrystal structure of glucagon analog with 4-bromo-phenylalanine substitutions at position 6 and 22 in space group I41 at 1.65 A resolution

Function Ontology

Hormonal / Endocrine

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC153H167N43O22S1

DescriptionPDB structure; X-ray @1.65Å

        HSQGTYTSDYSKYLDSRRAQDYVQWLMNT
    

Molecular Weight3514.75 Da

Isoelectric Point (pI)7.62

Net Charge (pH 7.0)0.09

Net Charge (pH 7.4) 0.02

Charge Density (pH 7.0) 0.0030

GRAVY Index-1.27

Hydrophobic Moment 0.15

Boman Index-0.24

Instability Index51.44

Aliphatic Index 40.34

Aromaticity 0.2069

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11460.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1341.87

LogP 0.56

H-bond Donors 30.0

H-bond Acceptors 53.0

Rotatable Bonds 59.0

Heavy Atoms 221.0

Ring Count 7.0

Amide Bonds 59.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0431315 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [other]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Hormonal / Endocrine

MethodX-ray