Peptide Database

Peptide NameNMR Structure of the ECD1 of CRF-R1 in complex with a peptide agonist

Function Ontology

Hormonal / Endocrine

Standard StatusStandard

Sequence Length84 amino acids

Chemical FormulaC400H446N116O43S6

DescriptionPDB structure; NMR

        LQDQHCESLSLASNISGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNE
    

Molecular Weight9272.24 Da

Isoelectric Point (pI)4.88

Net Charge (pH 7.0)-2.28

Net Charge (pH 7.4) -2.83

Charge Density (pH 7.0) -0.0271

GRAVY Index-0.26

Hydrophobic Moment 0.08

Boman Index0.02

Instability Index56.23

Aliphatic Index 76.67

Aromaticity 0.1071

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3296.27

LogP 2.76

H-bond Donors 67.0

H-bond Acceptors 132.0

Rotatable Bonds 149.0

Heavy Atoms 576.0

Ring Count 15.0

Amide Bonds 169.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0431309 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [other]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Hormonal / Endocrine

MethodNMR