Peptide Database

Peptide NameCrystal structure of Glucagon-Like Peptide-1 in complex with the extracellular domain of the Glucagon-Like Peptide-1 Receptor

Function Ontology

Hormonal / Endocrine

Standard StatusStandard

Sequence Length126 amino acids

Chemical FormulaC654H712N180O71S7

DescriptionPDB structure; X-ray @2.1Å

        GSHMRPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDLFCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDLSECEESKRGERSSPEEQLLFLY
    

Molecular Weight14724.19 Da

Isoelectric Point (pI)4.79

Net Charge (pH 7.0)-5.17

Net Charge (pH 7.4) -5.79

Charge Density (pH 7.0) -0.0411

GRAVY Index-0.81

Hydrophobic Moment 0.07

Boman Index-0.12

Instability Index79.73

Aliphatic Index 51.83

Aromaticity 0.1508

Extinction Coeff. Reduced 45950.00

Extinction Coeff. Oxidized 46325.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5107.58

LogP 14.97

H-bond Donors 108.0

H-bond Acceptors 201.0

Rotatable Bonds 245.0

Heavy Atoms 930.0

Ring Count 37.0

Amide Bonds 243.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0431306 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [other]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Hormonal / Endocrine

MethodX-ray