Peptide Database

Peptide NameExtracellular domain of GLP-1 receptor in complex with GLP-1 variant Ala8Cys/Thr11Cys

Function Ontology

Hormonal / Endocrine

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC150H164N40O15S2

DescriptionPDB structure; X-ray @2.0Å

        HCEGCFTSDVSSYLEGQAAKEFIAWLVKGRG
    

Molecular Weight3389.77 Da

Isoelectric Point (pI)5.42

Net Charge (pH 7.0)-1.03

Net Charge (pH 7.4) -1.25

Charge Density (pH 7.0) -0.0332

GRAVY Index-0.11

Hydrophobic Moment 0.06

Boman Index0.10

Instability Index13.46

Aliphatic Index 66.13

Aromaticity 0.1613

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1159.63

LogP 4.30

H-bond Donors 25.0

H-bond Acceptors 48.0

Rotatable Bonds 59.0

Heavy Atoms 212.0

Ring Count 6.0

Amide Bonds 57.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0431300 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [other]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Hormonal / Endocrine

MethodX-ray