Peptide Database

Peptide NameExtracellular domain of GLP-1 receptor in complex with GLP-1 variant Ala8Hcs/Thr11Hcs

Function Ontology

Hormonal / Endocrine

Standard StatusStandard

Sequence Length116 amino acids

Chemical FormulaC597H649N167O68S6

DescriptionPDB structure; X-ray @1.8Å

        RPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDLFCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDLSECEESKRGERSSPEE
    

Molecular Weight13533.78 Da

Isoelectric Point (pI)4.64

Net Charge (pH 7.0)-5.26

Net Charge (pH 7.4) -5.82

Charge Density (pH 7.0) -0.0454

GRAVY Index-0.94

Hydrophobic Moment 0.09

Boman Index-0.16

Instability Index84.74

Aliphatic Index 46.21

Aromaticity 0.1379

Extinction Coeff. Reduced 44460.00

Extinction Coeff. Oxidized 44835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4792.25

LogP 9.32

H-bond Donors 104.0

H-bond Acceptors 186.0

Rotatable Bonds 226.0

Heavy Atoms 856.0

Ring Count 34.0

Amide Bonds 222.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0431295 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [other]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Hormonal / Endocrine

MethodX-ray