Peptide Database

Peptide NameCryo-EM structure of neuropeptide FF receptor 2 in the ligand-free state with BRIL fusion, anti-BRIL Fab, and nanobody

Function Ontology

Neurological / Signaling

Standard StatusStandard

Sequence Length215 amino acids

Chemical FormulaC1035H1183N275O122S5

DescriptionPDB structure; EM @2.91Å

        SDIQMTQSPSSLSASVGDRVTITCRASQSVSSAVAWYQQKPGKAPKLLIYSASSLYSGVPSRFSGSRSGTDFTLTISSLQPEDFATYYCQQYLYYSLVTFGQGTKVEIKRTVAAPSVFIFPPSDSQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGE
    

Molecular Weight23460.84 Da

Isoelectric Point (pI)8.44

Net Charge (pH 7.0)2.94

Net Charge (pH 7.4) 2.47

Charge Density (pH 7.0) 0.0137

GRAVY Index-0.37

Hydrophobic Moment 0.08

Boman Index-0.01

Instability Index53.70

Aliphatic Index 69.35

Aromaticity 0.1116

Extinction Coeff. Reduced 28880.00

Extinction Coeff. Oxidized 29130.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8218.16

LogP 3.24

H-bond Donors 159.0

H-bond Acceptors 347.0

Rotatable Bonds 381.0

Heavy Atoms 1459.0

Ring Count 36.0

Amide Bonds 427.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0431252 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [other]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Neurological / Signaling

MethodEM