Peptide Database

Peptide NameCryo-EM structure of neuropeptide FF receptor 2 in the ligand-free state with BRIL fusion, anti-BRIL Fab, and nanobody

Function Ontology

Neurological / Signaling

Standard StatusStandard

Sequence Length229 amino acids

Chemical FormulaC1089H1204N284O109S5

DescriptionPDB structure; EM @2.91Å

        EISEVQLVESGGGLVQPGGSLRLSCAASGFNVVDFSLHWVRQAPGKGLEWVAYISSSSGSTSYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCARWGYWPGEPWWKAFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKS
    

Molecular Weight24300.87 Da

Isoelectric Point (pI)8.11

Net Charge (pH 7.0)2.03

Net Charge (pH 7.4) 1.52

Charge Density (pH 7.0) 0.0089

GRAVY Index-0.13

Hydrophobic Moment 0.02

Boman Index0.12

Instability Index39.02

Aliphatic Index 72.31

Aromaticity 0.1223

Extinction Coeff. Reduced 58900.00

Extinction Coeff. Oxidized 59150.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8178.96

LogP 4.99

H-bond Donors 159.0

H-bond Acceptors 348.0

Rotatable Bonds 381.0

Heavy Atoms 1523.0

Ring Count 49.0

Amide Bonds 435.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0431251 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [other]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Neurological / Signaling

MethodEM