Peptide Database

Peptide NameNeuropeptide Y Y1 Receptor (NPY1R) in Complex with G Protein and its endogeneous Peptide-Agonist Neuropeptide Y (NPY)

Function Ontology

Neurological / Signaling

Standard StatusStandard

Sequence Length259 amino acids

Chemical FormulaC1228H1341N339O120S10

DescriptionPDB structure; EM @3.2Å

        DVQLVESGGGLVQPGGSRKLSCSASGFAFSSFGMHWVRQAPEKGLEWVAYISSGSGTIYYADTVKGRFTISRDDPKNTLFLQMTSLRSEDTAMYYCVRSIYYYGSSPFDFWGQGTTLTVSSGGGGSGGGGSGGGGSDIVMTQATSSVPVTPGESVSISCRSSKSLLHSNGNTYLYWFLQRPGQSPQLLIYRMSNLASGVPDRFSGSGSGTAFTLTISRLEAEDVGVYYCMQHLEYPLTFGAGTKLELKAAAHHHHHHHH
    

Molecular Weight27755.59 Da

Isoelectric Point (pI)7.32

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) -0.18

Charge Density (pH 7.0) 0.0029

GRAVY Index-0.24

Hydrophobic Moment 0.02

Boman Index0.10

Instability Index46.79

Aliphatic Index 65.87

Aromaticity 0.1544

Extinction Coeff. Reduced 42860.00

Extinction Coeff. Oxidized 43110.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 9531.95

LogP -17.31

H-bond Donors 198.0

H-bond Acceptors 400.0

Rotatable Bonds 468.0

Heavy Atoms 1744.0

Ring Count 54.0

Amide Bonds 484.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0431249 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [other]

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Neurological / Signaling

MethodEM