Peptide Database

Peptide NameCASP8 and FADD-like apoptosis regulator

Function Ontology

Apoptosis

Standard StatusStandard

Sequence Length480 amino acids

Chemical FormulaC2460H2992N680O238S25

DescriptionStandard

        MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLYRVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYMGRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGTSYRNVLQAAIQKSLKDPSNNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIPEERYKMKSKPLGICLIIDCIGNETELLRDTFTSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVYGVDQTHSGLPLHHIRRMFMGDSCPYLAGKPKMFFIQNYVVSEGQLEDSSLLEVDGPAMKNVEFKAQKRGLCTVHREADFFWSLCTADMSLLEQSHSSPSLYLQCLSQKLRQERKRPLLDLHIELNGYMYDWNSRVSAKEKYYVWLQHTLRKKLILSYT
    

Molecular Weight55343.44 Da

Isoelectric Point (pI)7.82

Net Charge (pH 7.0)3.79

Net Charge (pH 7.4) 2.11

Charge Density (pH 7.0) 0.0079

GRAVY Index-0.35

Hydrophobic Moment 0.03

Boman Index-0.06

Instability Index52.72

Aliphatic Index 96.62

Aromaticity 0.1062

Extinction Coeff. Reduced 41830.00

Extinction Coeff. Oxidized 42455.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 18806.75

LogP -157.59

H-bond Donors 354.0

H-bond Acceptors 770.0

Rotatable Bonds 1000.0

Heavy Atoms 3444.0

Ring Count 70.0

Amide Bonds 957.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0431123 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [other]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Apoptosis