Peptide Database

Peptide NameDual specificity mitogen-activated protein kinase kinase 5

Function Ontology

Metal binding

Standard StatusStandard

Sequence Length448 amino acids

Chemical FormulaC2242H2638N600O207S23

DescriptionStandard

        MLWLALGPFPAMENQVLVIRIKIPNSGAVDWTVHSGPQLLFRDVLDVIGQVLPEATTTAFEYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGLKVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISICTEFMDGGSLDVYRKMPEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQIQKNQGSLMPLQLLQCIVDEDSPVLPVGEFSEPFVHFITQCMRKQPKERPAPEELMGHPFIVQFNDGNAAVVSMWVCRALEERRSQQGPP
    

Molecular Weight50111.16 Da

Isoelectric Point (pI)5.94

Net Charge (pH 7.0)-5.49

Net Charge (pH 7.4) -6.65

Charge Density (pH 7.0) -0.0122

GRAVY Index-0.15

Hydrophobic Moment 0.06

Boman Index0.06

Instability Index46.29

Aliphatic Index 91.99

Aromaticity 0.1049

Extinction Coeff. Reduced 51340.00

Extinction Coeff. Oxidized 51715.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 16642.71

LogP -134.87

H-bond Donors 299.0

H-bond Acceptors 682.0

Rotatable Bonds 883.0

Heavy Atoms 3134.0

Ring Count 80.0

Amide Bonds 875.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0431105 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [other]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Metal binding