Peptide Database

Peptide NameVascular endothelial growth factor A, long form

Function Ontology

Regulatory peptide ▸ Cell signaling / Growth factor signaling

Therapeutic / Biomedical activity ▸ Regenerative medicine ▸ Tissue repair / Regeneration

Wound healing/Regeneration ▸ Angiogenesis modulation

Standard StatusStandard

Sequence Length395 amino acids

Chemical FormulaC1857H2182N598O173S26

DescriptionStandard

        MTDRQTDTAPSPSYHLLPGRRRTVDAAASRGQGPEPAPGGGVEGVGARGVALKLFVQLLGCSRFGGAVVRAGEAEPSGAARSASSGREEPQPEEGEEEEEKEEERGPQWRLGARKPGSWTGEAAVCADSAPAARAPQALARASGRGGRVARRGAEESGPPHSPSRRGSASRAGPGRASETMNFLLSWVHWSLALLLYLHHAKWSQAAPMAEGGGQNHHEVVKFMDVYQRSYCHPIETLVDIFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIKPHQGQHIGEMSFLQHNKCECRPKKDRARQEKKSVRGKGKGQKRKRKKSRYKSWSVPCGPCSERRKHLFVQDPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR
    

Molecular Weight43596.82 Da

Isoelectric Point (pI)8.99

Net Charge (pH 7.0)17.03

Net Charge (pH 7.4) 14.89

Charge Density (pH 7.0) 0.0431

GRAVY Index-0.86

Hydrophobic Moment 0.01

Boman Index-0.21

Instability Index61.06

Aliphatic Index 52.68

Aromaticity 0.0835

Extinction Coeff. Reduced 43430.00

Extinction Coeff. Oxidized 44555.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 15940.58

LogP -150.90

H-bond Donors 349.0

H-bond Acceptors 623.0

Rotatable Bonds 803.0

Heavy Atoms 2724.0

Ring Count 68.0

Amide Bonds 745.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0431089 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [other]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Angiogenesis Tissue repair / Regeneration Growth factor