Peptide Database

Peptide NameKunitz-type protease inhibitor 2

Function Ontology

Enzyme / Catalytic activity ▸ Protease

Enzyme modulation ▸ Enzyme inhibition ▸ Inhibitor

Standard StatusStandard

Sequence Length252 amino acids

Chemical FormulaC1226H1428N360O117S19

DescriptionStandard

        MAQLCGLRRSRAFLALLGSLLLSGVLAADRERSIHDFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENATGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRCFRQQENPPLPLGSKVVVLAGLFVMVLILFLGASMVYLIRVARRNQERALRTVWSSGDDKEQLVKNTYVL
    

Molecular Weight28227.88 Da

Isoelectric Point (pI)8.10

Net Charge (pH 7.0)5.39

Net Charge (pH 7.4) 4.21

Charge Density (pH 7.0) 0.0214

GRAVY Index-0.25

Hydrophobic Moment 0.07

Boman Index-0.05

Instability Index58.20

Aliphatic Index 77.38

Aromaticity 0.1032

Extinction Coeff. Reduced 36900.00

Extinction Coeff. Oxidized 37650.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 9856.40

LogP -17.06

H-bond Donors 206.0

H-bond Acceptors 396.0

Rotatable Bonds 479.0

Heavy Atoms 1748.0

Ring Count 38.0

Amide Bonds 500.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0431061 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [other]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Enzyme inhibitory Protease inhibitor Enzyme inhibitory Serine protease inhibitor