Peptide Database

Peptide NameNoggin

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ Inhibitor

Standard StatusStandard

Sequence Length232 amino acids

Chemical FormulaC1145H1348N328O88S15

DescriptionStandard

        MERCPSLGVTLYALVVVLGLRATPAGGQHYLHIRPAPSDNLPLVDLIEHPDPIFDPKEKDLNETLLRSLLGGHYDPGFMATSPPEDRPGGGGGAAGGAEDLAELDQLLRQRPSGAMPSEIKGLEFSEGLAQGKKQRLSKKLRRKLQMWLWSQTFCPVLYAWNDLGSRFWPRYVKVGSCFSKRSCSVPEGMVCKPSKSVHLTVLRWRCQRRGGQRCGWIPIQYPIISECKCSC
    

Molecular Weight25773.62 Da

Isoelectric Point (pI)8.86

Net Charge (pH 7.0)8.85

Net Charge (pH 7.4) 7.75

Charge Density (pH 7.0) 0.0381

GRAVY Index-0.34

Hydrophobic Moment 0.11

Boman Index-0.02

Instability Index73.74

Aliphatic Index 80.69

Aromaticity 0.0991

Extinction Coeff. Reduced 41940.00

Extinction Coeff. Oxidized 42565.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8644.16

LogP -5.04

H-bond Donors 179.0

H-bond Acceptors 349.0

Rotatable Bonds 464.0

Heavy Atoms 1621.0

Ring Count 49.0

Amide Bonds 431.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0431060 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [other]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Enzyme inhibitory