Peptide Database

Peptide NamePigment epithelium-derived factor

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ Inhibitor

Standard StatusStandard

Sequence Length418 amino acids

Chemical FormulaC2087H2493N545O205S9

DescriptionStandard

        MQALVLLLCIGALLGHSSCQNPASPPEEGSPDPDSTGALVEEEDPFFKVPVNKLAAAVSNFGYDLYRVRSSTSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDLISSPDIHGTYKELLDTVTAPQKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLTGNPRLDLQEINNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTSEFIHDIDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLFDSPDFSKITGKPIKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLFIGKILDPRGP
    

Molecular Weight46311.62 Da

Isoelectric Point (pI)5.92

Net Charge (pH 7.0)-4.42

Net Charge (pH 7.4) -5.14

Charge Density (pH 7.0) -0.0106

GRAVY Index-0.16

Hydrophobic Moment 0.02

Boman Index0.04

Instability Index40.82

Aliphatic Index 97.03

Aromaticity 0.0933

Extinction Coeff. Reduced 31400.00

Extinction Coeff. Oxidized 31525.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 15414.45

LogP -121.38

H-bond Donors 274.0

H-bond Acceptors 635.0

Rotatable Bonds 801.0

Heavy Atoms 2899.0

Ring Count 71.0

Amide Bonds 809.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0431053 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [other]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Enzyme inhibitory