Peptide Database

Peptide NameGrowth/differentiation factor 2

Function Ontology

Immunology ▸ Cytokine / receptor signaling modulation

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Regulatory peptide ▸ Cell signaling / Growth factor signaling

Therapeutic / Biomedical activity ▸ Regenerative medicine ▸ Tissue repair / Regeneration

Wound healing/Regeneration ▸ Angiogenesis modulation

Standard StatusStandard

Sequence Length429 amino acids

Chemical FormulaC2087H2419N575O218S17

DescriptionStandard

        MCPGALWVALPLLSLLAGSLQGKPLQSWGRGSAGGNAHSPLGVPGGGLPEHTFNLKMFLENVKVDFLRSLNLSGVPSQDKTRVEPPQYMIDLYNRYTSDKSTTPASNIVRSFSMEDAISITATEDFPFQKHILLFNISIPRHEQITRAELRLYVSCQNHVDPSHDLKGSVVIYDVLDGTDAWDSATETKTFLVSQDIQDEGWETLEVSSAVKRWVRSDSTKSKNKLEVTVESHRKGCDTLDISVPPGSRNLPFFVVFSNDHSSGTKETRLELREMISHEQESVLKKLSKDGSTEAGESSHEEDTDGHVAAGSTLARRKRSAGAGSHCQKTSLRVNFEDIGWDSWIIAPKEYEAYECKGGCFFPLADDVTPTKHAIVQTLVHLKFPTKVGKACCVPTKLSPISVLYKDDMGVPTLKYHYEGMSVAECGCR
    

Molecular Weight47319.92 Da

Isoelectric Point (pI)6.01

Net Charge (pH 7.0)-7.21

Net Charge (pH 7.4) -8.87

Charge Density (pH 7.0) -0.0168

GRAVY Index-0.37

Hydrophobic Moment 0.05

Boman Index-0.01

Instability Index52.17

Aliphatic Index 78.14

Aromaticity 0.1096

Extinction Coeff. Reduced 53400.00

Extinction Coeff. Oxidized 54025.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 16238.63

LogP -131.23

H-bond Donors 312.0

H-bond Acceptors 671.0

Rotatable Bonds 814.0

Heavy Atoms 2952.0

Ring Count 77.0

Amide Bonds 826.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0431042 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [other]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Angiogenesis Immunomodulatory Cytokine Tissue repair / Regeneration Growth factor