Peptide Database

Peptide NameGlia-derived nexin

Function Ontology

Enzyme / Catalytic activity ▸ Protease

Enzyme modulation ▸ Enzyme inhibition ▸ Inhibitor

Standard StatusStandard

Sequence Length398 amino acids

Chemical FormulaC1990H2381N529O165S15

DescriptionStandard

        MNWHLPLFLLASVTLPSICSHFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITTGSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP
    

Molecular Weight44001.69 Da

Isoelectric Point (pI)9.73

Net Charge (pH 7.0)10.59

Net Charge (pH 7.4) 9.75

Charge Density (pH 7.0) 0.0266

GRAVY Index0.05

Hydrophobic Moment 0.04

Boman Index0.11

Instability Index41.35

Aliphatic Index 99.42

Aromaticity 0.1005

Extinction Coeff. Reduced 40450.00

Extinction Coeff. Oxidized 40700.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 14303.84

LogP -96.67

H-bond Donors 242.0

H-bond Acceptors 597.0

Rotatable Bonds 744.0

Heavy Atoms 2742.0

Ring Count 69.0

Amide Bonds 788.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0431026 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [other]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Enzyme inhibitory Protease inhibitor Enzyme inhibitory Serine protease inhibitor