Peptide Database

Peptide NameCyclin-dependent kinase 4 inhibitor B

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ Inhibitor

Standard StatusStandard

Sequence Length138 amino acids

Chemical FormulaC627H751N203O57S6

DescriptionStandard

        MREENKGMPSGGGSDEGLASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEERGHRDVAGYLRTATGD
    

Molecular Weight14721.49 Da

Isoelectric Point (pI)6.07

Net Charge (pH 7.0)-1.68

Net Charge (pH 7.4) -1.99

Charge Density (pH 7.0) -0.0122

GRAVY Index-0.32

Hydrophobic Moment 0.11

Boman Index-0.06

Instability Index24.80

Aliphatic Index 85.65

Aromaticity 0.0580

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5375.01

LogP -1.19

H-bond Donors 111.0

H-bond Acceptors 203.0

Rotatable Bonds 263.0

Heavy Atoms 917.0

Ring Count 15.0

Amide Bonds 257.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0431023 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [other]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Enzyme inhibitory