Peptide Database

Peptide NameKallistatin

Function Ontology

Enzyme / Catalytic activity ▸ Protease

Enzyme modulation ▸ Enzyme inhibition ▸ Inhibitor

Standard StatusStandard

Sequence Length427 amino acids

Chemical FormulaC2217H2584N578O194S13

DescriptionStandard

        MHLIDYLLLLLVGLLALSHGQLHVEHDGESCSNSSHQQILETGEGSPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGKVVDPTKP
    

Molecular Weight48541.36 Da

Isoelectric Point (pI)7.50

Net Charge (pH 7.0)1.57

Net Charge (pH 7.4) 0.27

Charge Density (pH 7.0) 0.0037

GRAVY Index-0.07

Hydrophobic Moment 0.04

Boman Index0.08

Instability Index35.41

Aliphatic Index 96.14

Aromaticity 0.1546

Extinction Coeff. Reduced 42860.00

Extinction Coeff. Oxidized 42985.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 15745.69

LogP -95.78

H-bond Donors 277.0

H-bond Acceptors 653.0

Rotatable Bonds 834.0

Heavy Atoms 3041.0

Ring Count 86.0

Amide Bonds 845.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0431021 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [other]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Enzyme inhibitory Protease inhibitor Enzyme inhibitory Serine protease inhibitor