Peptide Database

Peptide NamePlasminogen activator inhibitor 1

Function Ontology

Enzyme / Catalytic activity ▸ Protease

Enzyme modulation ▸ Enzyme inhibition ▸ Inhibitor

Standard StatusStandard

Sequence Length402 amino acids

Chemical FormulaC2032H2372N540O178S19

DescriptionStandard

        MQMSPALTCLVLGLALVFGEGSAVHHPPSYVAHLASDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP
    

Molecular Weight45059.46 Da

Isoelectric Point (pI)6.75

Net Charge (pH 7.0)-0.85

Net Charge (pH 7.4) -1.67

Charge Density (pH 7.0) -0.0021

GRAVY Index-0.06

Hydrophobic Moment 0.06

Boman Index0.09

Instability Index35.33

Aliphatic Index 87.76

Aromaticity 0.1269

Extinction Coeff. Reduced 35410.00

Extinction Coeff. Oxidized 35410.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 14711.95

LogP -96.36

H-bond Donors 254.0

H-bond Acceptors 610.0

Rotatable Bonds 767.0

Heavy Atoms 2815.0

Ring Count 77.0

Amide Bonds 792.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0431020 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [other]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Enzyme inhibitory Protease inhibitor Enzyme inhibitory Serine protease inhibitor