Peptide Database

Peptide NameGremlin-1

Function Ontology

Immunology ▸ Cytokine / receptor signaling modulation

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Standard StatusStandard

Sequence Length184 amino acids

Chemical FormulaC891H1083N271O86S13

DescriptionStandard

        MSRTAYTVGALLLLLGTLLPAAEGKKKGSQGAIPPPDKAQHNDSEQTQSPQQPGSRNRGRGQGRGTAMPGEEVLESSQEALHVTERKYLKRDWCKTQPLKQTIHEEGCNSRTIINRFCYGQCNSFYIPRHIRKEEGSFQSCSFCKPKKFTTMMVTLNCPELQPPTKKKRVTRVKQCRCISIDLD
    

Molecular Weight20696.55 Da

Isoelectric Point (pI)9.77

Net Charge (pH 7.0)12.82

Net Charge (pH 7.4) 11.86

Charge Density (pH 7.0) 0.0697

GRAVY Index-0.80

Hydrophobic Moment 0.08

Boman Index-0.19

Instability Index57.35

Aliphatic Index 60.43

Aromaticity 0.0761

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7439.57

LogP 0.72

H-bond Donors 156.0

H-bond Acceptors 300.0

Rotatable Bonds 388.0

Heavy Atoms 1289.0

Ring Count 28.0

Amide Bonds 359.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0430961 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [other]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Immunomodulatory Cytokine