Peptide Database

Peptide NameSerpin B6

Function Ontology

Enzyme / Catalytic activity ▸ Protease

Enzyme modulation ▸ Enzyme inhibition ▸ Inhibitor

Standard StatusStandard

Sequence Length376 amino acids

Chemical FormulaC1896H2211N491O196S26

DescriptionStandard

        MDVLAEANGTFALNLLKTLGKDNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFNKSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETTDLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKADFSGMSQTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFFIQHSKTNGILFCGRFSSP
    

Molecular Weight42621.44 Da

Isoelectric Point (pI)4.97

Net Charge (pH 7.0)-10.86

Net Charge (pH 7.4) -11.68

Charge Density (pH 7.0) -0.0289

GRAVY Index-0.22

Hydrophobic Moment 0.02

Boman Index0.02

Instability Index35.91

Aliphatic Index 75.98

Aromaticity 0.1170

Extinction Coeff. Reduced 28420.00

Extinction Coeff. Oxidized 28795.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 14157.93

LogP -79.38

H-bond Donors 252.0

H-bond Acceptors 592.0

Rotatable Bonds 764.0

Heavy Atoms 2642.0

Ring Count 57.0

Amide Bonds 748.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0430925 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [other]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Enzyme inhibitory Protease inhibitor Enzyme inhibitory Serine protease inhibitor