Peptide Database

Peptide NameVitamin K-dependent protein C

Function Ontology

Binding / Molecular interaction

Binding / Molecular interaction ▸ Calcium binding

Enzyme modulation ▸ Enzyme inhibition ▸ Blood coagulation cascade inhibitor

Hemostasis

Standard StatusStandard

Sequence Length461 amino acids

Chemical FormulaC2290H2634N648O219S32

DescriptionStandard

        MWQLTSLLLFVATWGISGTPAPLDSVFSSSERAHQVLRIRKRANSFLEELRHSSLERECIEEICDFEEAKEIFQNVDDTLAFWSKHVDGDQCLVLPLEHPCASLCCGHGTCIDGIGSFSCDCRSGWEGRFCQREVSFLNCSLDNGGCTHYCLEEVGWRRCSCAPGYKLGDDLLQCHPAVKFPCGRPWKRMEKKRSHLKRDTEDQEDQVDPRLIDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHCMDESKKLLVRLGEYDLRRWEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAERELNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNMVSENMLCAGILGDRQDACEGDSGGPMVASFHGTWFLVGLVSWGEGCGLLHNYGVYTKVSRYLDWIHGHIRDKEAPQKSWAP
    

Molecular Weight52070.75 Da

Isoelectric Point (pI)5.81

Net Charge (pH 7.0)-11.79

Net Charge (pH 7.4) -14.74

Charge Density (pH 7.0) -0.0256

GRAVY Index-0.35

Hydrophobic Moment 0.04

Boman Index-0.02

Instability Index48.82

Aliphatic Index 80.13

Aromaticity 0.1215

Extinction Coeff. Reduced 94420.00

Extinction Coeff. Oxidized 95920.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 17672.32

LogP -133.84

H-bond Donors 356.0

H-bond Acceptors 718.0

Rotatable Bonds 921.0

Heavy Atoms 3245.0

Ring Count 91.0

Amide Bonds 893.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0430906 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [other]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Binding / Molecular interaction Calcium binding Hemostasis Hemostasis Blood coagulation