Peptide Database

Peptide NameAnnexin A8

Function Ontology

Binding / Molecular interaction

Binding / Molecular interaction ▸ Calcium binding

Binding / Molecular interaction ▸ Metal binding

Enzyme modulation ▸ Enzyme inhibition ▸ Blood coagulation cascade inhibitor

Hemostasis

Standard StatusStandard

Sequence Length327 amino acids

Chemical FormulaC1626H1943N435O183S15

DescriptionStandard

        MAWWKSWIEQEGVTVKSSSHFNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQFGKDLTETLKSELSGKFERLIVALMYPPYRYEAKELHDAMKGLGTKEGVIIEILASRTKNQLREIMKAYEEDYGSSLEEDIQADTSGYLERILVCLLQGSRDDVSSFVDPGLALQDAQDLYAAGEKIRGTDEMKFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQNLHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMIMEDTSGDYKNALLSLVGSDP
    

Molecular Weight36880.60 Da

Isoelectric Point (pI)5.41

Net Charge (pH 7.0)-6.66

Net Charge (pH 7.4) -7.37

Charge Density (pH 7.0) -0.0204

GRAVY Index-0.40

Hydrophobic Moment 0.06

Boman Index-0.04

Instability Index41.20

Aliphatic Index 85.35

Aromaticity 0.0979

Extinction Coeff. Reduced 37360.00

Extinction Coeff. Oxidized 37610.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 12726.54

LogP -59.86

H-bond Donors 241.0

H-bond Acceptors 524.0

Rotatable Bonds 673.0

Heavy Atoms 2287.0

Ring Count 41.0

Amide Bonds 646.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0430892 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [other]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Binding / Molecular interaction Calcium binding Hemostasis Hemostasis Blood coagulation Metal binding