Peptide Database

Peptide NameCathepsin K

Function Ontology

Bioactive

Standard StatusStandard

Sequence Length329 amino acids

Chemical FormulaC1643H1890N454O158S16

DescriptionStandard

        MWGLKVLLLPVVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM
    

Molecular Weight36965.60 Da

Isoelectric Point (pI)8.47

Net Charge (pH 7.0)6.25

Net Charge (pH 7.4) 5.12

Charge Density (pH 7.0) 0.0190

GRAVY Index-0.51

Hydrophobic Moment 0.07

Boman Index-0.02

Instability Index35.05

Aliphatic Index 76.44

Aromaticity 0.1246

Extinction Coeff. Reduced 76320.00

Extinction Coeff. Oxidized 76820.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 12714.45

LogP -61.94

H-bond Donors 243.0

H-bond Acceptors 517.0

Rotatable Bonds 659.0

Heavy Atoms 2313.0

Ring Count 62.0

Amide Bonds 651.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0430881 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [other]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Bioactive