Peptide Database

Peptide NameThyrotropin-releasing hormone receptor

Function Ontology

Hormonal / Endocrine

Standard StatusStandard

Sequence Length398 amino acids

Chemical FormulaC2066H2424N506O171S26

DescriptionStandard

        MENETVSELNQTQLQPRAVVALEYQVVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSLYCMLWFFLLDLNISTYKDAIVISCGYKISRNYYSPIYLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNTNLNVNTSNRCFNSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKPTEKPANYSVALNYSVIKESDHFSTELDDITVTDTYLSATKVSFDDTCLASEVSFSQS
    

Molecular Weight45084.40 Da

Isoelectric Point (pI)8.09

Net Charge (pH 7.0)6.43

Net Charge (pH 7.4) 4.96

Charge Density (pH 7.0) 0.0162

GRAVY Index0.43

Hydrophobic Moment 0.02

Boman Index0.21

Instability Index33.71

Aliphatic Index 108.19

Aromaticity 0.1357

Extinction Coeff. Reduced 65780.00

Extinction Coeff. Oxidized 66655.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 13914.68

LogP -56.01

H-bond Donors 241.0

H-bond Acceptors 606.0

Rotatable Bonds 715.0

Heavy Atoms 2795.0

Ring Count 74.0

Amide Bonds 806.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0430856 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [other]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Hormonal / Endocrine