Peptide Database

Peptide NameThyroid hormone receptor alpha

Function Ontology

Binding / Molecular interaction ▸ Metal binding

Standard StatusStandard

Sequence Length490 amino acids

Chemical FormulaC2371H2843N689O248S32

DescriptionStandard

        MEQKPSKVECGSDPEENSARSPDGKRKRKNGQCSLKTSMSGYIPSYLDKDEQCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHIATEAHRSTNAQGSHWKQRRKFLPDDIGQSPIVSMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKREQLKNGGLGVVSDAIFELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFEHYVNHRKHNIPHFWPKLLMKEREVQSSILYKGAAAEGRPGGSLGVHPEGQQLLGMHVVQGPQVRQLEQQLGEAGSLQGPVLQHQSPKSPQQRLLELLHRSGILHARAVCGEDDSSEADSPSSSEEEPEVCEDLAGNAASP
    

Molecular Weight54814.97 Da

Isoelectric Point (pI)6.40

Net Charge (pH 7.0)-3.84

Net Charge (pH 7.4) -6.19

Charge Density (pH 7.0) -0.0078

GRAVY Index-0.54

Hydrophobic Moment 0.00

Boman Index-0.11

Instability Index61.90

Aliphatic Index 77.82

Aromaticity 0.0796

Extinction Coeff. Reduced 31400.00

Extinction Coeff. Oxidized 32525.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 19253.48

LogP -192.93

H-bond Donors 376.0

H-bond Acceptors 792.0

Rotatable Bonds 1000.0

Heavy Atoms 3400.0

Ring Count 68.0

Amide Bonds 959.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0430832 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [other]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Metal binding