Peptide Database

Peptide NameProenkephalin-A

Function Ontology

Neurological / Signaling

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length268 amino acids

Chemical FormulaC1345H1550N372O144S21

DescriptionStandard

        MARFLRLCTWLLVLGSCLLATVQAECSQDCAKCSYHLVSPGDINFLACTLECEGQMPSHKIWETCKDLLQVSKPEFPCDSINMFKDSNKQDESHLLAKKYGGFMKRYGGFMKKMDELYPVEPEEEANGGEILAKKYGGFMKKDADEGDTLANSSDLLKELLGTGDNRAREGRHQESTDNDDNMSKRYGGFMRGLKRSPQVEDEAKELQKRYGGFMRRVGRPEWWMDYQKRYGGFLKRFAESLPSDEEAESYSKEVPEIEKRYGGFMRF
    

Molecular Weight30732.56 Da

Isoelectric Point (pI)5.64

Net Charge (pH 7.0)-4.16

Net Charge (pH 7.4) -5.15

Charge Density (pH 7.0) -0.0155

GRAVY Index-0.77

Hydrophobic Moment 0.08

Boman Index-0.14

Instability Index66.00

Aliphatic Index 57.54

Aromaticity 0.1194

Extinction Coeff. Reduced 38390.00

Extinction Coeff. Oxidized 38890.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 10699.81

LogP -27.25

H-bond Donors 217.0

H-bond Acceptors 433.0

Rotatable Bonds 587.0

Heavy Atoms 1918.0

Ring Count 46.0

Amide Bonds 516.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0430751 VERIFIED: NO

Provenance & Taxonomy

OrganismMesocricetus auratus [other]

Tax ID10036

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Neurological / Signaling Neuropeptide