Peptide Database

Peptide NameProenkephalin-A

Function Ontology

Neurological / Signaling

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length268 amino acids

Chemical FormulaC1332H1542N374O144S16

DescriptionStandard

        MARLLRLCTWLVALGPGLLATVQAECSQDCAACSYRLVRPGDLNFLACTLECEGQLPSLKIWETCKDLLQVSKQELPQEGASSLRESGKQDESHLLSKKYGGFMKRYGGFMKKVDELYPVEPEEEANGGEILTKRYGGFMKKDAEDGDALANSSDLLKELLGTGDDRDRENHHQEGGDSDEGVSKRYGGFMRGLKRSPQVEDEAKELQKRYGGFMRRVGRPEWWMDYQKRYGGFLKRFAEFLPSDEEGESYSKEVPEMEKRYGGFMRF
    

Molecular Weight30436.05 Da

Isoelectric Point (pI)5.21

Net Charge (pH 7.0)-6.12

Net Charge (pH 7.4) -6.90

Charge Density (pH 7.0) -0.0228

GRAVY Index-0.77

Hydrophobic Moment 0.07

Boman Index-0.15

Instability Index58.19

Aliphatic Index 62.61

Aromaticity 0.1082

Extinction Coeff. Reduced 38390.00

Extinction Coeff. Oxidized 38765.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 10779.47

LogP -33.21

H-bond Donors 224.0

H-bond Acceptors 425.0

Rotatable Bonds 591.0

Heavy Atoms 1908.0

Ring Count 43.0

Amide Bonds 508.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0430746 VERIFIED: NO

Provenance & Taxonomy

OrganismCavia porcellus [other]

Tax ID10141

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Neurological / Signaling Neuropeptide