Peptide Database

Peptide NameProenkephalin-A

Function Ontology

Neurological / Signaling

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length269 amino acids

Chemical FormulaC1359H1561N371O149S19

DescriptionStandard

        MAQFLRLCIWLLALGSCLLATVQADCSQDCAKCSYRLVRPGDINFLACTLECEGQLPSFKIWETCKDLLQVSKPEFPWDNIDMYKDSSKQDESHLLAKKYGGFMKRYGGFMKKMDELYPVEPEEEANGGEILAKRYGGFMKKDADEGDTLANSSDLLKELLGTGDNRAKDSHQQESTNNDEDSTSKRYGGFMRGLKRSPQLEDEAKELQKRYGGFMRRVGRPEWWMDYQKRYGGFLKRFAESLPSDEEGESYSKEVPEMEKRYGGFMRF
    

Molecular Weight30931.67 Da

Isoelectric Point (pI)5.19

Net Charge (pH 7.0)-5.28

Net Charge (pH 7.4) -6.09

Charge Density (pH 7.0) -0.0196

GRAVY Index-0.80

Hydrophobic Moment 0.05

Boman Index-0.15

Instability Index58.74

Aliphatic Index 58.07

Aromaticity 0.1190

Extinction Coeff. Reduced 45380.00

Extinction Coeff. Oxidized 45880.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 10799.40

LogP -28.07

H-bond Donors 219.0

H-bond Acceptors 434.0

Rotatable Bonds 591.0

Heavy Atoms 1934.0

Ring Count 47.0

Amide Bonds 519.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0430718 VERIFIED: NO

Provenance & Taxonomy

OrganismRattus norvegicus [other]

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Neurological / Signaling Neuropeptide