Peptide Database

Peptide NameProenkephalin-A

Function Ontology

Neurological / Signaling

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length267 amino acids

Chemical FormulaC1348H1574N374O147S19

DescriptionStandard

        MARFLTLCTWLLLLGPGLLATVRAECSQDCATCSYRLVRPADINFLACVMECEGKLPSLKIWETCKELLQLSKPELPQDGTSTLRENSKPEESHLLAKRYGGFMKRYGGFMKKMDELYPMEPEEEANGSEILAKRYGGFMKKDAEEDDSLANSSDLLKELLETGDNRERSHHQDGSDNEEEVSKRYGGFMRGLKRSPQLEDEAKELQKRYGGFMRRVGRPEWWMDYQKRYGGFLKRFAEALPSDEEGESYSKEVPEMEKRYGGFMRF
    

Molecular Weight30786.65 Da

Isoelectric Point (pI)5.25

Net Charge (pH 7.0)-6.11

Net Charge (pH 7.4) -6.90

Charge Density (pH 7.0) -0.0229

GRAVY Index-0.80

Hydrophobic Moment 0.06

Boman Index-0.16

Instability Index60.76

Aliphatic Index 61.42

Aromaticity 0.1086

Extinction Coeff. Reduced 38390.00

Extinction Coeff. Oxidized 38765.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 10771.34

LogP -29.88

H-bond Donors 222.0

H-bond Acceptors 430.0

Rotatable Bonds 593.0

Heavy Atoms 1925.0

Ring Count 45.0

Amide Bonds 509.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0430695 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [other]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Neurological / Signaling Neuropeptide