Peptide Database

Peptide NameTLR4 inhibitory peptide

Function Ontology

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Immunology ▸ Inflammation modulation ▸ Anti-inflammatory

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC95H118N14O1S1

DescriptionStandard

        MIFLIFLIFLIFLI
    

Molecular Weight1756.32 Da

Isoelectric Point (pI)6.01

Net Charge (pH 7.0)-0.00

Net Charge (pH 7.4) -0.01

Charge Density (pH 7.0) -0.0001

GRAVY Index3.63

Hydrophobic Moment 0.05

Boman Index1.18

Instability Index9.29

Aliphatic Index 250.71

Aromaticity 0.2857

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 327.35

LogP 17.05

H-bond Donors 2.0

H-bond Acceptors 16.0

Rotatable Bonds 30.0

Heavy Atoms 112.0

Ring Count 4.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0430656 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Immunomodulatory Anti-inflammatory

TargetTLR4/MD-2 complex

Activity3.2 μM

MethodIC50