Peptide Database

Peptide NameRGD-4C

Function Ontology

Anticancer ▸ Tumor Homing Peptide

Delivery / Targeting

Standard StatusStandard

Sequence Length10 amino acids

Chemical FormulaC45H51N15O4S4

DescriptionStandard

        CCCRGDWKCT
    

Molecular Weight1174.40 Da

Isoelectric Point (pI)7.69

Net Charge (pH 7.0)0.75

Net Charge (pH 7.4) 0.42

Charge Density (pH 7.0) 0.0750

GRAVY Index-0.39

Hydrophobic Moment 0.29

Boman Index-0.25

Instability Index33.11

Aliphatic Index 0.00

Aromaticity 0.1000

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5750.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 416.14

LogP 0.20

H-bond Donors 14.0

H-bond Acceptors 19.0

Rotatable Bonds 20.0

Heavy Atoms 70.0

Ring Count 2.0

Amide Bonds 17.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0430654 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Delivery / Targeting Tumor homing

Targetαvβ3 integrin (tumor vasculature)

Activity3.5 nM

MethodKd