Peptide Database

Peptide NameAP2S1 Colorectal cancer antigenic peptide

Function Ontology

Anticancer ▸ Cancer antigenic

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC53H60N12O4

DescriptionStandard

        AYLEAIHKF
    

Molecular Weight1091.26 Da

Isoelectric Point (pI)7.75

Net Charge (pH 7.0)0.09

Net Charge (pH 7.4) 0.03

Charge Density (pH 7.0) 0.0099

GRAVY Index0.31

Hydrophobic Moment 0.50

Boman Index0.28

Instability Index48.91

Aliphatic Index 108.89

Aromaticity 0.3333

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 338.03

LogP 5.12

H-bond Donors 6.0

H-bond Acceptors 14.0

Rotatable Bonds 18.0

Heavy Atoms 70.0

Ring Count 3.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0430645 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Cancer antigenic

Targetpeptide / Colorectal cancer

MethodT cell recognition assay

PaperShinkawa T, Tokita S, Nakatsugawa M, Kikuchi Y, Kanaseki T, Torigoe T. Characterization of CD8+ T-cell responses to non-anchor-type HLA class I neoantigens with single amino-acid substitutions. Oncoimmunology. 2021 10(1):1870062. (PMID: 33537174) PMID33537174 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33537174/