Peptide Database

Peptide NameETV6-AML1 fusion protein acute lymphoblastic leukemia antigenic peptide

Function Ontology

Anticancer ▸ Cancer antigenic

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC68H90N22O5S2

DescriptionStandard

        IGRIAECILGMNPSR
    

Molecular Weight1629.95 Da

Isoelectric Point (pI)8.93

Net Charge (pH 7.0)0.94

Net Charge (pH 7.4) 0.85

Charge Density (pH 7.0) 0.0625

GRAVY Index0.29

Hydrophobic Moment 0.27

Boman Index0.07

Instability Index75.23

Aliphatic Index 110.67

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 589.66

LogP 0.10

H-bond Donors 14.0

H-bond Acceptors 23.0

Rotatable Bonds 32.0

Heavy Atoms 101.0

Ring Count 1.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0430643 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Cancer antigenic

Targetpeptide / acute lymphoblastic leukemia

MethodT cell recognition assay

PaperYun C, Senju S, Fujita H, Tsuji Y, Irie A, Matsushita S, Nishimura Y. Augmentation of immune response by altered peptide ligands of the antigenic peptide in a human CD4+ T-cell clone reacting to TEL/AML1 fusion protein. Tissue Antigens. 1999 Aug, 54(2):153-61. (PMID: 10488742) PMID10488742 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10488742/