Peptide Database

Peptide Nameneo-PAP melanoma antigenic peptide

Function Ontology

Anticancer ▸ Cancer antigenic

Anticancer ▸ melanoma

Standard StatusStandard

Sequence Length11 amino acids

Chemical FormulaC58H87N19O4

DescriptionStandard

        RVIKNSIRLTL
    

Molecular Weight1312.60 Da

Isoelectric Point (pI)12.49

Net Charge (pH 7.0)3.00

Net Charge (pH 7.4) 2.99

Charge Density (pH 7.0) 0.2725

GRAVY Index0.26

Hydrophobic Moment 0.72

Boman Index-0.15

Instability Index1.37

Aliphatic Index 168.18

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 499.79

LogP 1.58

H-bond Donors 12.0

H-bond Acceptors 18.0

Rotatable Bonds 26.0

Heavy Atoms 82.0

Ring Count 0.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0430638 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Cancer antigenic

Targetautologous tumor cells / melanoma

MethodT cell recognition assay

PaperTopalian SL, Gonzales MI, Ward Y, Wang X, Wang RF. Revelation of a cryptic major histocompatibility complex class II-restricted tumor epitope in a novel RNA-processing enzyme. Cancer Res. 2002 Oct 1, 62(19):5505-9. (PMID: 12359760) PMID12359760 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12359760/