Peptide Database

Peptide NameARTC1 melanoma antigenic peptide

Function Ontology

Anticancer ▸ Cancer antigenic

Anticancer ▸ melanoma

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC84H87N17O11

DescriptionStandard

        YSVYFNLPADTIYTN
    

Molecular Weight1780.93 Da

Isoelectric Point (pI)3.00

Net Charge (pH 7.0)-1.00

Net Charge (pH 7.4) -1.01

Charge Density (pH 7.0) -0.0669

GRAVY Index-0.07

Hydrophobic Moment 0.14

Boman Index0.23

Instability Index-1.37

Aliphatic Index 78.00

Aromaticity 0.2667

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 592.52

LogP 4.01

H-bond Donors 11.0

H-bond Acceptors 25.0

Rotatable Bonds 24.0

Heavy Atoms 114.0

Ring Count 5.0

Amide Bonds 29.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0430635 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Cancer antigenic

Targetautologous tumor cells / melanoma

MethodT cell recognition assay

PaperWang HY, Peng G, Guo Z, Shevach EM, Wang RF. Recognition of a new ARTC1 peptide ligand uniquely expressed in tumor cells by antigen-specific CD4+ regulatory T cells. J Immunol. 2005 Mar 1, 174(5):2661-70. (PMID: 15728473) PMID15728473 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15728473/