Peptide Database

Peptide NameCLPP melanoma antigenic peptide

Function Ontology

Anticancer ▸ Cancer antigenic

Anticancer ▸ melanoma

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC50H70N12O3

DescriptionStandard

        ILDKVLVHL
    

Molecular Weight1049.31 Da

Isoelectric Point (pI)7.82

Net Charge (pH 7.0)0.09

Net Charge (pH 7.4) 0.03

Charge Density (pH 7.0) 0.0099

GRAVY Index1.52

Hydrophobic Moment 0.48

Boman Index0.44

Instability Index11.42

Aliphatic Index 237.78

Aromaticity 0.1111

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 317.80

LogP 5.35

H-bond Donors 5.0

H-bond Acceptors 13.0

Rotatable Bonds 19.0

Heavy Atoms 66.0

Ring Count 1.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0430633 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Cancer antigenic

Targetautologous tumor cells / melanoma

MethodT cell recognition assay

PaperCorbière V, Chapiro J, Stroobant V, Ma W, Lurquin C, Lethé B, van Baren N, Van den Eynde BJ, Boon T, Coulie PG. Antigen spreading contributes to MAGE vaccination-induced regression of melanoma metastases. Cancer Res. 2011 Feb 15, 71(4):1253-62. (PMID: 21216894) PMID21216894 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21216894/