Peptide Database

Peptide NameChgkaalac

Function Ontology

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Beauverolide

Standard StatusStandard

Sequence Length7 amino acids

Chemical FormulaC29H36N10O1S2

DescriptionStandard

        CHGKLAC
    

Molecular Weight730.90 Da

Isoelectric Point (pI)8.16

Net Charge (pH 7.0)0.96

Net Charge (pH 7.4) 0.75

Charge Density (pH 7.0) 0.1378

GRAVY Index0.44

Hydrophobic Moment 0.24

Boman Index0.12

Instability Index78.84

Aliphatic Index 70.00

Aromaticity 0.1429

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 248.67

LogP 0.39

H-bond Donors 7.0

H-bond Acceptors 12.0

Rotatable Bonds 13.0

Heavy Atoms 44.0

Ring Count 1.0

Amide Bonds 11.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0427678 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Structure & Mods

Configcyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

DisulfideTerminal cysteine disulfide cyclization in the transformed nonapeptide

Other ModsCyclicPepedia normalized one-letter core CHGKLAC maps to experimental transformed sequence CHGKAALAC

Bio-Activity Profile

Function

Antiviral Andes virus infection inhibition Surface glycoprotein binding

TargetAndes virus strain CHI-7913; surface glycoproteins Gn/Gc; Vero E6 cells

Activity27.22 %

MethodANDV infection inhibition by peptide-bearing phage; immunofluorescence assay (IFA)