Peptide Database

Peptide NameCkfplnaac

Function Ontology

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Beauverolide

Standard StatusStandard

Sequence Length7 amino acids

Chemical FormulaC36H43N9O2S2

DescriptionStandard

        CKFPLNC
    

Molecular Weight824.02 Da

Isoelectric Point (pI)8.15

Net Charge (pH 7.0)0.87

Net Charge (pH 7.4) 0.71

Charge Density (pH 7.0) 0.1248

GRAVY Index0.37

Hydrophobic Moment 0.31

Boman Index0.10

Instability Index31.97

Aliphatic Index 55.71

Aromaticity 0.1429

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 254.29

LogP 1.40

H-bond Donors 6.0

H-bond Acceptors 12.0

Rotatable Bonds 14.0

Heavy Atoms 51.0

Ring Count 2.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0427677 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Structure & Mods

Configcyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

DisulfideTerminal cysteine disulfide cyclization in the transformed nonapeptide

Other ModsCyclicPepedia normalized one-letter core CKFPLNC maps to experimental transformed sequence CKFPLNAAC

Bio-Activity Profile

Function

Antiviral Andes virus infection inhibition Surface glycoprotein binding

TargetAndes virus strain CHI-7913; surface glycoproteins Gn/Gc; Vero E6 cells

Activity22.89 %

MethodANDV infection inhibition by peptide-bearing phage; immunofluorescence assay (IFA)