Peptide Database

Peptide NameCehlshaac

Function Ontology

Antiviral

Binding / Molecular interaction ▸ Surface glycoprotein binding

Standard StatusStandard

Sequence Length7 amino acids

Chemical FormulaC32H35N11O4S2

DescriptionStandard

        CEHLSHC
    

Molecular Weight827.93 Da

Isoelectric Point (pI)6.01

Net Charge (pH 7.0)-0.94

Net Charge (pH 7.4) -1.21

Charge Density (pH 7.0) -0.1346

GRAVY Index-0.27

Hydrophobic Moment 0.36

Boman Index-0.01

Instability Index-2.20

Aliphatic Index 55.71

Aromaticity 0.2857

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 300.07

LogP 0.67

H-bond Donors 8.0

H-bond Acceptors 14.0

Rotatable Bonds 13.0

Heavy Atoms 50.0

Ring Count 2.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0427673 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Structure & Mods

Configcyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

DisulfideTerminal cysteine disulfide cyclization in the transformed nonapeptide

Other ModsCyclicPepedia normalized one-letter core CEHLSHC maps to experimental transformed sequence CEHLSHAAC

Bio-Activity Profile

Function

Antiviral Andes virus infection inhibition Surface glycoprotein binding

TargetAndes virus strain CHI-7913; surface glycoproteins Gn/Gc; Vero E6 cells

Activity38.47 %

MethodANDV infection inhibition by peptide-bearing phage; immunofluorescence assay (IFA)