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MYP_174052
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Basic Information
Dermaseptin-PD-2
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
33 amino acids
C139H237N41O41S
Standard
Sequence
GMWSKIKNAGKAAAKAAAKAAGKAALDAVSEAI
Physicochemical Analysis
3170.68 Da
10.00
3.76
3.54
0.1139
0.14
0.63
0.12
5.24
83.64
0.0303
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1324.58
-14.69
46.0
46.0
110.0
222.0
2.0
33.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0038794 VERIFIED: YES
Provenance & Taxonomy
Pachymedusa dacnicolor [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Pseudomonas aeruginosa
2.5 μM
MIC
PaperTwo Novel Dermaseptin-Like Antimicrobial Peptides with Anticancer Activities from the Skin Secretion of Pachymedusa dacnicolor
RECORD: Rec_0068860 VERIFIED: YES
Provenance & Taxonomy
Animalia [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID27187467 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27187467/
RECORD: Rec_0090190 VERIFIED: YES
Provenance & Taxonomy
Animalia [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID27187467 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27187467/
RECORD: Rec_0096093 VERIFIED: YES
Provenance & Taxonomy
Pachymedusa dacnicolor [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus NCTC 10788
5 μM
MIC
PMID27187467 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27187467/
RECORD: Rec_0151675 VERIFIED: YES
Provenance & Taxonomy
Pachymedusa dacnicolor [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli NCTC 10418
5 μM
MIC
PMID27187467 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27187467/
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