Peptide Database

Peptide NameT-198

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor

Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC171H286N48O57

DescriptionStandard

        SVALDPIDISIELNKAKSDLEESKEWIRRSNQKL
    

Molecular Weight3926.39 Da

Isoelectric Point (pI)5.09

Net Charge (pH 7.0)-1.53

Net Charge (pH 7.4) -1.75

Charge Density (pH 7.0) -0.0450

GRAVY Index-0.74

Hydrophobic Moment 0.63

Boman Index-0.21

Instability Index65.48

Aliphatic Index 106.18

Aromaticity 0.0294

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1750.02

LogP -17.40

H-bond Donors 60.0

H-bond Acceptors 56.0

Rotatable Bonds 139.0

Heavy Atoms 276.0

Ring Count 3.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0211739 VERIFIED: YES

Provenance & Taxonomy

OrganismHuman parainfluenza virus 3 [Virus]

FamilyVirus-derived peptide

Tax ID11216;0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Fusion inhibitor

TargetHuman parainfluenza virus type 3 (Fusion); Vero

MethodImmunoprecipitation

PaperMethods for the inhibition of respiratory syncytial virus transmission | Dani Paul Bolognesi, Thomas James Matthews, Carl T. Wild, Shawn O'Lin Barney,Dennis Michael Lambert, Stephen Robert Petteway | Trimeris, Inc., Durham NC | Patent:US6440656 Evidence URLhttps://patents.google.com/patent/US6440656/en PatentUS6440656

RECORD: Rec_0385982 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 70.6%, E 0.0%, T 0.0%, C 29.4% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antiviral Antimicrobial