Peptide Database

Peptide NameRegenerating islet-derived protein 3-gamma (REG-3-gamma) (Pancreatitis-associated protein 3) (Regenerating islet-derived protein III-gamma) (Reg III-gamma) [Cleaved into: Regenerating islet-derived protein 3-gamma 16.5 kDa form; Regenerating islet-derived protein 3-gamma 15 kDa form]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus

Binding / Molecular interaction ▸ Carbohydrate-binding peptide ▸ Lectin

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length174 amino acids

Chemical FormulaC843H1294N232O257S11

DescriptionStandard

        MLPRVALTTMSWMLLSSLMLLSQVQGEDAKEDVPTSRISCPKGSRAYGSYCYALFSVSKSWFDADLACQKRPSGHLVSVLSGSEASFVSSLIKSSGNSGQNVWIGLHDPTLGQEPNRGGWEWSNADVMNYFNWETNPSSVSGSHCGTLTRASGFLRWRENNCISELPYVCKFKA
    

Molecular Weight19143.41 Da

Isoelectric Point (pI)7.60

Net Charge (pH 7.0)0.72

Net Charge (pH 7.4) 0.23

Charge Density (pH 7.0) 0.0041

GRAVY Index-0.24

Hydrophobic Moment 0.48

Boman Index0.05

Instability Index40.97

Aliphatic Index 71.15

Aromaticity 0.1034

Extinction Coeff. Reduced 45950.00

Extinction Coeff. Oxidized 46325.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7835.87

LogP -89.52

H-bond Donors 282.0

H-bond Acceptors 272.0

Rotatable Bonds 619.0

Heavy Atoms 1343.0

Ring Count 36.0

Amide Bonds 187.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0420388 VERIFIED: YES

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-MRSA Anti-Gram-positive Lectin Non-hemolytic

TargetListeria monocytogenes (Gram-positive)