Peptide Database

Peptide NameDefensin 6

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC440H726N122O136S8

DescriptionStandard

        MKKLVLLSALVLLALQVQAEPTPKTDEGTKTDEQPGKEDQVVSVSIEGQGDPAFQDAVLRDLKCFCRAKSCNWGEGIMGICNKRYGSLILCCR
    

Molecular Weight10157.73 Da

Isoelectric Point (pI)6.20

Net Charge (pH 7.0)-0.54

Net Charge (pH 7.4) -0.88

Charge Density (pH 7.0) -0.0059

GRAVY Index-0.14

Hydrophobic Moment 0.78

Boman Index-0.01

Instability Index32.38

Aliphatic Index 91.18

Aromaticity 0.0430

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4171.53

LogP -42.33

H-bond Donors 147.0

H-bond Acceptors 144.0

Rotatable Bonds 347.0

Heavy Atoms 706.0

Ring Count 9.0

Amide Bonds 100.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0362559 VERIFIED: NO

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyDefensin

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal